Issue Highlights Phosphorylation-mediated regulation of GSK3β Inhibition of Hedgehog pathway inhibits clonogenic growth of primary AML cells Mechanisms of action of oncolytic virus therapy

نویسندگان

  • Yusuke Nakamura
  • Hiroyuki Mano
  • Takashi Sugimura
  • Yutaka Kawakami
  • Kohei Miyazono
  • Hitoshi Nakagama
  • Tomoki Naoe
  • Masahide Takahashi
  • Richard J. Ablin
  • Hiroyuki Aburatani
  • Koichi Akashi
  • Hideyuki Akaza
  • Tetsuo Akimoto
  • Hirotoshi Akita
  • Shin-ichi Akiyama
  • Tetsu Akiyama
  • Yuichi Ando
  • Daisuke Aoki
  • Masahiro Aoki
  • Hirofumi Arakawa
  • Suk-Chul Bae
  • Yung-Jue Bang
  • William T. Beck
  • Maarten C. Bosland
  • Xuetao Cao
  • Anthony T.C. Chan
  • Ceshi Chen
  • Yao-Tseng Chen
  • Shigeru Chiba
  • Toshihiko Doi
  • Tommaso A. Dragani
  • Keigo Endo
  • Hiroyasu Esumi
  • Soldano Ferrone
  • Naoya Fujita
  • Toshiyoshi Fujiwara
  • Yasuhiro Fujiwara
  • Kiyoko Fukami
  • Masashi Fukayama
  • Yoichi Furukawa
  • Koichi Goto
  • Noriko Goto
  • Michael M. Gottesman
  • Parry Guilford
  • Mingzhou Guo
  • Koichi Hagiwara
  • Nobuyuki Hamajima
  • Eiji Hara
  • Hideyoshi Harashima
  • Curtis C. Harris
  • Kiyohiko Hatake
  • Masanori Hatakeyama
  • Carl-Henrik Heldin
  • Shigeki Higashiyama
  • Okio Hino
  • Atsushi Hirao
  • Masahiro Hiraoka
  • Seiichi Hirota
  • Akira Horii
  • Chung-cheng Hsieh
  • Kay Huebner
  • Hidenori Ichijo
  • Shinsuke Iida
  • Hiroaki Ikeda
  • Katsumi Imaida
  • Takeshi Imamura
  • Issei Imoto
  • Masaya Imoto
  • Masaki Inagaki
  • Johji Inazawa
  • Jun-ichiro Inoue
  • Manami Inoue
  • Masahiro Inoue
  • Satoshi Inoue
  • Takashi Ishida
  • Genichiro Ishii
  • Hideshi Ishii
  • Fuyuki Ishikawa
  • Yuichi Ishikawa
  • Chikashi Ishioka
  • Kyogo Itoh
  • Hirotaka Iwase
  • David H. Johnson
  • Kenji Kadomatsu
  • Takehiko Kamijo
  • Yae Kanai
  • Yuzuru Kanakura
  • Atsushi Kaneda
  • Yasufumi Kaneda
  • Shuichi Kaneko
  • Mari Kannagi
  • Reiji Kannagi
  • Masanori Kasahara
  • Toyomasa Katagiri
  • Kazunori Kataoka
  • Mitsuyasu Kato
  • Elliott Kieff
  • Akira Kikuchi
  • Chul-Woo Kim
  • Kyu-Won Kim
  • Seong-Jin Kim
  • Shinya Kimura
  • Tomohiro Kinoshita
  • Issay Kitabayashi
  • Yuko Kitagawa
  • Toshio Kitamura
  • Chifumi Kitanaka
  • Hitoshi Kiyoi
  • Tohru Kiyono
  • Shinae Kizaka-Kondoh
  • Alexander Knuth
  • Kimitoshi Kohno
  • Takashi Kohno
  • Kazuhiko Koike
  • Yutaka Kondo
  • Koji Kono
  • Mineo Kurokawa
  • Michihiko Kuwano
  • Kiyotaka Kuzushima
  • Jin Li
  • Jincai Luo
  • Yoshihiko Maehara
  • Taira Maekawa
  • Yoshiro Maru
  • Kenkichi Masutomi
  • Michiyuki Matsuda
  • Yasuhiro Matsumura
  • Keitaro Matsuo
  • Masao Matsuoka
  • Yoshio Miki
  • Hironobu Minami
  • Kinuko Mitani
  • Tetsuya Mitsudomi
  • Kiyoshi Miyagawa
  • Satoru Miyano
  • Keiji Miyazawa
  • Eiji Miyoshi
  • Morito Monden
  • Masaki Mori
  • Eiichi Morii
  • Hozumi Motohashi
  • Yoshinori Murakami
  • Yohji Nagashima
  • Chisato Nagata
  • Mikihiko Naito
  • Yusaku Nakabeppu
  • Kei Nakachi
  • Hidewaki Nakagawa
  • Kazuhiko Nakagawa
  • Masayuki Nakagawa
  • Akira Nakagawara
  • Shigeo Nakamura
  • Takuro Nakamura
  • Makoto Nakanishi
  • Ichiro Nakano
  • Mitsuyoshi Nakao
  • Tetsuya Nakatsura
  • Eiichi Nakayama
  • Keiichi Nakayama
  • Toshinori Nakayama
  • Yoshiro Niitsu
  • Toshiro Niki
  • Hiroyoshi Nishikawa
  • Yasuharu Nishimura
  • Kazuto Nishio
  • Tetsuo Noda
  • Masayuki Noguchi
  • Shinzaburo Noguchi
  • Norio Nonomura
  • Atsushi Ochiai
  • Takahiro Ochiya
  • Tatsuya Oda
  • Yoshinao Oda
  • Katsuhiro Ogawa
  • Osamu Ogawa
  • Seishi Ogawa
  • Yuichiro Ohe
  • Hiroko Ohgaki
  • Miki Ohira
  • Koichi Ohshima
  • Atsushi Ohtsu
  • Futoshi Okada
  • Yasunori Okada
  • Koji Okamoto
  • Hiroyuki Osada
  • Masanobu Oshima
  • Mototsugu Oya
  • Keiya Ozawa
  • Pier Paolo Pandolfi
  • Jae-Gahb Park
  • Manuel Perucho
  • You-Lin Qiao
  • Roger Reddel
  • Shigehira Saji
  • Ryuichi Sakai
  • Toshiyuki Sakai
  • Michiie Sakamoto
  • Jacques Samarut
  • Yasutsuna Sasaki
  • Hironobu Sasano
  • Noriyuki Sato
  • Yasufumi Sato
  • Hideyuki Saya
  • Motoharu Seiki
چکیده

ing and Indexing Services The Journal is indexed by AgBiotech News & Information (CABI), BIOBASE: Current Awareness in Biological Sciences (Elsevier), Biological Abstracts (Thomson Reuters), BIOSIS Previews (Thomson Reuters), CAS: Chemical Abstracts Service (ACS), CSA Biological Sciences Database (ProQuest), CSA Oncogenes & Growth Factors Abstracts (ProQuest), Current

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Elevation of cAMP Levels Inhibits Doxorubicin-Induced Apoptosis in Pre- B ALL NALM- 6 Cells Through Induction of BAD Phosphorylation and Inhibition of P53 Accumulation

Recognition of the molecular mechanisms of cAMP action against DNA damage-induced apoptosis can be useful to improve the efficacy of DNA damaging therapeutic agents. Considering the critical role of bcl-2-associated death promoter (BAD) and p53 proteins in DNA damage -induced apoptosis, the aim of this study was to assess the effect of cAMP-elevating agents on these proteins in doxorubicin-trea...

متن کامل

Investigating the role of signaling pathways and cancer stem cells in esophageal cancer with a therapeutic approach

Esophageal cancer (EC) is the sixth main cause of cancer death worldwide. Important genes associated with esophageal cancer include FOXO3, AKT, and GSK3β. Excessive FOXO3 expression inhibits the proliferation of cancer cells. The expression of AKT is involved in controlling cell growth in tumors. GSK3β activity is higher in cancer tissues. Given the effective role of cancer stem cells (CSCs) in...

متن کامل

Nanocurcumin-Mediated Down-Regulation of Telomerase Via Stimulating TGFβ1 Signaling Pathway in Hepatocellular Carcinoma Cells

Background: Curcumin, extracted from turmeric, represents enormous potential to serve as an anticancer agent. Telomerase is viewed as a prominent molecular target of curcumin, and transforming growth factor-β1 (TGFβ1) has proven to be a major inhibitory signaling pathway for telomerase activity. In the current study, we aimed to explore suppressive effects of nanocurcumin on telomeras...

متن کامل

Developing oncolytic Herpes simplex virus type 1 through UL39 knockout by CRISPR-Cas9

Objective(s): Oncolytic Herpes simplex virus type 1 (HSV-1) has emerged as a promising strategy for cancer therapy. However, development of novel oncolytic mutants has remained a major challenge owing to low efficiency of conventional genome editing methods. Recently, CRISPR-Cas9 has revolutionized genome editing.Materials and Methods: I...

متن کامل

The Role of Fetuin-A in Diabetes and Obesity: The Mechanism and Action

Fetuin-A is a phosphorylated glycoprotein produced by liver.It by binding to calcium ion inhibits ectopic calcium deposition and protects vascular calcification. Fetuin-A acts as a multifactorial protein and its role has been documented from brain development to bone remodeling and immune function, regulation of insulin activity, hepatocyte growth factor activity and inhibition lymphocyte blast...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2016